日本未熟児新生児学会雑誌 25(1):27-30;2013  |
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日本未熟児新生児学会雑誌 第25巻第1号 27~30頁(2013年) |
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受付日:平成24.03.21 |
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受理日:平成24.06.06 |
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鎖骨部腫瘤を契機に発見された亜急性骨髄炎の新生児例 |
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A Very-Low-Birth-Weight Infant with Subacute Osteomyelitis |
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昭和大学 医学部 小児科学教室 |
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Department of Pediatrics, Showa University School of Medicine |
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櫻井基一郎・山川琢司・水野克己・板橋家頭夫 |
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Motoichiro SAKURAI,Takuji YAMAKAWA,Katsumi MIZUNO,Kazuo ITAHASHI |
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Key Words:subacute osteomyelitis,neonate
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症例は,在胎33 週1 日,出生体重1,413g の女児。入院時に左手背よりPI カテーテル ® (以下PIC)を挿入した。日齢9 にPIC を抜去したが,日齢17 に左肘部に膿瘍形成が認められ,日齢31 に左鎖骨部の腫瘤が出現した。鎖骨部X 線写真では鎖骨に嚢胞状の病変が認められた。MRI では肩鎖関節や胸鎖関節は正常所見であった。他部位の病変検索のための骨シンチグラムでは,同部位の集積が認められるのみであった。腫瘤発見時に全身状態は良好であり炎症所見もなかったため,外科的処置や抗菌薬の投与は行わず経過を観察した。2 週間ほどで腫瘤性病変は縮小傾向を示した。近年,非定型的な経過を示す骨髄炎が散見されており,亜急性骨髄炎と称されている。本疾患の発症は緩徐であり全身所見に欠け特徴的な検査所見もないことから発見,診断までに時間を要することが多い。PIC感染や膿瘍を生じた児では骨変化にも留意し経過観察を行うことが必要であると考える。 |
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The patient was born at 33 weeks and 1 day of gestation. Her birth weight was 1,413g. We inserted a PI catheter Ⓡ
from the dorsum side of her left hand to the cubitus. The catheter was removed on nine days of her age. An abscess was
found at cubitus on 17 days of age. On 31 days of age, her left clavicle area was swollen and X-ray revealed a cyst in the
clavicle bone. The MRI of humeral articulation and acromioclavicular joint did not detect any abnormal intensity. A bone
scintigram showed accumulation of technetium-99m only at the clavicular region. Because her general condition was good
and blood test did not detect any inflammatory findings on 31 days of age, we did not perform surgical interventions or
antibiotic treatment. A swelling of left clavicle returned to normal within 2 weeks. The clavicular X-rays demonstrated
improvement at that time. Recently, non-typical osteomyelitis called subacute osteomyelitis has been reported. The onset
is slow and quiet. In addition, there are no characteristic laboratory findings, therefore it is difficult to make correct
diagnosis. We conclude that it is necessary to evaluate bone radiographic changes after infection related to PI catheter Ⓡ
insertion. |
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