日本未熟児新生児学会雑誌 27(1):89-93;2015  |
 |
日本未熟児新生児学会雑誌 第27巻第1号 89 ~ 93頁(2015年) |
 |
受付日:平成26.02.03 |
 |
受理日:平成26.09.08 |
 |
胆嚢壁浮腫状肥厚を認めたヒトパレコウイルス3 型感染の1 新生児例 |
 |
A Neonatal Case of Human Parechovirus-3 Infection with Edema of the Gallbladder Wall |
 |
博愛会一関病院 小児科(現 天童市民病院 小児科) |
 |
Department of Pediatrics, Ichinoseki Hospital(presently known as Tendo City Hospital) |
 |
遠藤泰史 |
 |
Yasufumi ENDO |
 |
Key Words:human parechovirus 3(HPeV-3),edema of the gallbloadder wall,elevated levels of liver and muscle derived enzy,viral isolation from throat swab,systemic inflammatory response syndrome(SIRS)
|
 |
ヒトパレコウイルス(human parechovirus:HPeV)は主に小児の胃腸炎や呼吸器疾患から分離されるウイルスでありピコルナウイルス科パレコウイルス属に分類され,海外では乳幼児突然死症候群(sudden infant death syndrome:SIDS)の児から検出された報告もある。症例は正期産女児,日齢14 より発熱,哺乳不良をみとめ当院小児科に入院した。日齢15 より傾眠傾向,腹部膨満が出現した。検査において肝,筋逸脱酵素の上昇,腹部CT において胆嚢壁の浮腫状肥厚がみられた。高サイトカイン血症の様相を呈したためヒト免疫グロブリンを投与,その後速やかに解熱した。岩手県環境保健研究センターのウイルス分離にてHPeV3 型(HPeV-3)が咽頭ぬぐい液より検出された。
|
 |
Human parechoviruses(HPeV)belong to the genus Parechovirus in the Picornaviridae family and are primarily
isolated from infants with gastroenteritis and a respiratory disease. HPeV-3 is reported to be detected from sudden infant
deaths in some countries and requires careful attention. We present a case of a full-term girl who developed fever and
exhibited poor suckling at the age of 14 days;therefore, she was brought to the Department of Pediatrics at our hospital.
From day 2 of hospitalization, she received γ globulin for reducing somnolence and remittent fever. Tests revealed
elevated levels of liver- and muscle-derived enzymes, and abdominal CT showed edema surrounding the gallbladder wall.
Further, the fever rapidly decreased after the intravenous immunoglobulin administration. The virus was isolated from a
throat swab and was classified as HPeV-3. |
 |
(c)日本未熟児新生児学会 All Rights Reserved. |
 |