日本新生児成育医学会雑誌 34(1):101-105;2022  |
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日本新生児成育医学会雑誌 第34巻 第4号 101~ 105頁(2022年) |
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受付日:2021.07.26 |
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受理日:2021.12.14 |
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B 群連鎖球菌による新生児尿路感染症の1 例 |
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A Case of Neonatal Urinary Tract Infection Caused by Group B Streptococci |
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竹田綜合病院 小児科 |
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Department of Pediatrics,Takeda General Hospital |
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蛭田 俊・有賀裕道・市川弘隆・山元みいる・木下英俊・福田 豊・藤木伴男・長澤克俊 |
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Shun HIRUTA,Hiromichi ARIGA,Hirotaka ICHIKAWA,Miiru YAMAMOTO,
Hidetoshi KINOSHITA,Yutaka FUKUDA,Tomoo FUJIKI,Katsutoshi NAGASAWA |
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Key Words:Group B Streptococci,urinary tract infection,neonate,late-onset disease,vesicoureteral reflux |
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B 群連鎖球菌(GBS)は,新生児期から乳児期早期に髄膜炎や敗血症を来すことはよく知られている。今回,日齢
9 に発症したGBS による尿路感染症の1 例を経験したため報告する。症例は正期産の男児で出生体重3,113g,新生
児早期に感染症状なく日齢7 に退院した。日齢9 に発熱を主訴に当科を受診,炎症反応上昇あり髄液ならびに血液
を含む細菌培養検査実施後にセフトリアキソンならびにアンピシリンによる抗菌療法を開始した。尿検体よりGBS
が5×104/mL 認められ,GBS による尿路感染症と診断した。10 日間の抗菌療法で治癒した。膀胱造影ではgrade Ⅱ
の膀胱尿管逆流を認めたが抗菌薬の予防内服は行わなかった。新生児期のGBS 尿路感染症は非常に稀であり症状も
非特異的であるため,治療開始時に本疾患を念頭に置き検査することが重要である。 |
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It is well known that the Group B Streptococci( GBS) cause meningitis and sepsis from neonatal period to early infancy.
We present a case of GBS urinary tract infection that occurred in a nine-day-old baby boy. He was born after full-term
gestation with a birth weight of 3113g, and was discharged at seven days of age without symptoms of infection. At ninedays
old, he was admitted to our pediatric department with increased inflammatory symptoms. After performing bacterial
culture tests, including cerebrospinal fluid and blood, antimicrobial therapy with ceftriaxone and ampicillin was started.
A urine sample showed GBS of 5×104/mL, and he was diagnosed with a GBS urinary tract infection. The newborn was
cured after ten days of antimicrobial therapy. Cystography showed grade Ⅱ vesicoureteral reflux, but no antimicrobial
prophylaxis was provided. Neonatal GBS urinary tract infections are very rare and their symptoms are non-specific, and
therefore it is important to test with this disease in mind at the start of treatment. |
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